Polynucleotides

What Are Polynucleotides?

Polynucleotides are highly purified DNA fragments, most commonly derived from salmon or trout due to their strong biocompatibility with human tissue. When precisely injected into the skin, they act as powerful bio-stimulators.

Unlike dermal fillers, polynucleotides do not “fill” lines or reshape the face. Instead, they improve the condition of the skin itself by:

• Stimulating fibroblast activity.
• Increasing collagen and elastin production.
• Improving deep dermal hydration.
• Supporting tissue repair.
• Decreasing oxidative stress and inflammation.

The result is healthier, more resilient skin without an altered appearance.

Why Polynucleotides Work

Polynucleotides activate the body’s natural regenerative processes in a number of ways:

1. Collagen & Elastin Stimulation

They encourage fibroblasts (the cells that produce collagen and elastin) to increase their activity. Over time, this improves firmness, elasticity and structural strength.

2. Deep Skin Hydration

Polynucleotides attract and bind water molecules within the dermis, delivering hydration from within rather than sitting superficially on the skin.

3. Tissue Repair & Healing

By enhancing microcirculation and cellular turnover, Polynucleotides are especially effective for fragile, damaged or ageing skin.

4. Anti-Inflammatory & Antioxidant Support

Their antioxidant properties help to soothe inflammation while protecting against environmental stressors that accelerate the ageing process.

This multi-layered regenerative effect is why polynucleotides are increasingly used in preventive and corrective aesthetics at our Gravesend beauty clinic to deliver the best results and outcomes for our clients.

Best Treatment Areas

Polynucleotide injections can be used across multiple areas where skin quality improvement is required. These can include:

• Under-eye area (fine lines, crepey skin, dark circles).
• Full face (texture, laxity, dullness).
• Neck.
• Décolletage.
• Hands.
• Acne scarring.
• Post-inflammatory skin damage.

They are particularly well-suited to more delicate areas and where dermal fillers may be an unsuitable choice for an individual client.

Who Is Polynucleotide Treatment For?

Polynucleotides are ideal for individuals who want to:

• Improve early signs of ageing.
• Address fine lines and skin laxity.
• Restore hydration and radiance.
• Improve under-eye quality without adding volume.
• Strengthen fragile or thinning skin.
• Support long-term skin health.

Suitable for both men and women, this treatment can be used preventatively in younger patients or restoratively in more mature skin.

What to Expect

Treatment takes approximately 30–45 minutes. A topical anaesthetic may be applied for comfort.

For best results, a course of 2–3 sessions spaced 2–4 weeks apart is recommended. Maintenance treatments may be advised every 6–12 months, depending on individual skin goals.

Mild swelling, redness, or small injection-site bumps may occur and typically resolve within 24–72 hours. Downtime is minimal, and most patients resume normal activities shortly after treatment.

Results develop gradually as collagen production increases. Improvements in hydration may be noticeable within a few weeks, with continued skin strengthening over several months.

Benefits of Polynucleotides

• Stimulates collagen production.
• Improves skin firmness and elasticity.
• Boosts deep dermal hydration.
• Refines skin texture for a more youthful appearance.
• Brightens the under-eye area.
• Strengthens thin or fragile skin.
• Promotes long-term skin regeneration.
• Gives natural, subtle results.
• Offers minimal downtime.

Polynucleotides vs Dermal Fillers

Although often compared, polynucleotides and dermal fillers serve different purposes.

• Polynucleotides focus on improving skin quality by stimulating regeneration. Results develop gradually and enhance the integrity of the skin itself.
• Dermal fillers are designed to restore lost volume or reshape facial contours, delivering instant structural change.

Many patients benefit from a combined approach, harnessing the volumising and contouring benefits of dermal fillers with this regenerative treatment to enhance skin quality while addressing volume loss.

Why Choose Our Clinic for Skin Rejuvenation?

• Medically trained aesthetics practitioners.
• Premium injectable products.
• Bespoke treatment protocols.
• Evidence-based approach.
• UK-compliant clinical environment.
• Focus on natural, healthy skin outcomes.

If you’re ready for smoother, brighter, deeply hydrated skin, book a personalised consultation with us today. Skin boosters offer a refined, science-led approach to modern skin rejuvenation while delivering healthy radiance from within.

Our clinic is situated near Longfield mainline station, making us conveniently located for those from Dartford, Gravesend, Bexley, Bromley, Kent, Essex, London and surrounding areas situated customers seeking lip fillers, dermal fillers and Botox®.